Safety of Testosterone Therapy & Clueless Primary Care Physicians
Testosterone replacement therapy for hypogonadal men has been used for decades. However, there are still scores of primary care doctors spreading irresponsible misinformation regarding the safety of this treatment, particularly to elderly men who can benefit mightily from a balanced hormonal health.
A study was done with 255 men with an Average age of 60.6 ± 8.0 years, with testosterone levels between ≤ 3.5 ng/ml. They received parenteral (injectable) testosterone undecanoate.
After more than five years of monitored testosterone therapy , the study noted that a mere 3 out of 255 patients were diagnosed with prostate cancer. The study stated that “3/255 patients with prostate cancer does not suggest an increased risk of prostate cancer in elderly men on long-term testosterone treatment. Long-term treatment with testosterone undecanoate with monitoring according to the guidelines is acceptably safe.”
Now, according to cancer.org, “About 1 man in 6 will be diagnosed with prostate cancer during his lifetime.” They also stated, “Prostate cancer can be a serious disease, but most men diagnosed with prostate cancer do not die from it. In fact, more than 2.5 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.”
In over 50 years of studies and research, there has never been a connection between testosterone levels in men and prostate cancer growth. Moreover, a study from Harvard Medical School in 2006 concluded, “there is not now, nor has there ever been a scientific basis for the belief that testosterone causes prostate cancer to grow.”
Just more evidence that testosterone replacement therapy does not cause cancer or prostate cancer. We can’t explain why leagues of completely clueless primary care doctors still spread baseless accusations that TRT is unsafe.
http://www.cancer.org/cancer/prostateca … statistics
Boston Testosterone is a Testosterone Replacement , Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.
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See: Side-Effect Profile of Long-Term Treatment of Elderly Hypogonadal Men with Testosterone Undecanoate – Farid Saad, Ahmad Haider, Gheorghe Doros, Louis Gooren. Bayer Pharma AG, Berlin, Germany; Gulf Medical University School of Medicine, Ajman, United Arab Emirates; Private Practice, Bremerhaven, Germany; Public School of Health, Boston University, Boston, MA; VUMC Amsterdam, Amsterdam, Netherlands.
Testosterone; Male or Female you need it!
by: Michelle LeSueur
It is amazing how many people are suffering from low testosterone. What is concerning is how young they are both male and female. Many are in their 20′s and early 30′s. So I decided that I would write on this in hopes to enlighten people and give them a direction.
When you talk about testosterone we tend to think that it is a male hormone. Testosterone is considered a male hormone but both men and women have it. For men it is primarily produced in the testes, women only make one tenth of what men do and it is made in smaller amounts in the ovaries. Both male and female produce smaller amounts in the adrenal glands. Testosterone is the main component when it comes to a sex drive for both men and women.
Many people believe that low testosterone only affects older men but, According to the FDA, more than 4 million men suffer from low testosterone levels. Yet, 95 out of 100 men fail to seek treatment. Many believe that low hormone levels are just a part of getting older. What men and women don’t realize is if you replace your hormones with Bio-identical natural hormones you don’t have to age!!
Research shows that by the time we get to 70 and 80 there is an increased risk of obesity, brittle bones, muscle loss, impotence and you are at higher risk for a heart attack, because of low testosterone. When women finish menopause, they usually have low testosterone levels and it can be even worse for those using synthetic estrogen replacement. Many find they have no energy, muscle tone or libido. Testosterone increases the metabolic functions, which contribute to faster healing and lower total body fat.
If you are training and working to build muscle and shed fat, you need healthy testosterone levels. One of the first things many notice when their levels start to drop is midsection weight. Once levels have been restored many find that they are able to lose that unwanted belly fat.
When we are born we have so many fat cells. At puberty and for women, pregnancy are two times in your life that you can actually increase the amount of fat cells you have. Once you have increased fat cells you can never get rid of them. You are able to shrink them, but never get rid of them. These fat cells can expand mach larger than what they were originally if we over eat and need to store more and more fat. But again, you can shrink them. Hormones affect fat cells in two different ways, depending on the message they get. A lipolytic or beta hormone tells the body to in crease fat burning energy and lipogenic or alpha hormones tell the body to store fat. In different parts of our bodies we have alpha or beta-receptors and that is why it is easier to lose weight in some areas over others. The name of the game is for our fat cells to have more beta-receptors than alpha. By increasing testosterone, we increase beta-receptors. I have seen men with high cholesterol levels drop into normal range after they started replacing their testosterone.
Testosterone is necessary for sperm to mature and contributes to the overall quality of the sperm. In the last 15 years male infertility is on the rise. But here is the problem; it takes 3 months for sperm to develop verses one cycle with women, so male infertility is more of a problem than when a woman has fertility issues. There is a lot of research that supports that we are seeing a rise in this because of all the estrogen’s in our environment. You can find out more about environmental factors in the book, “ Willing to Change! Can You Beat Genetics ”.
So what are the symptoms of low testosterone?
Here is a little test to take, if you think you may have low levels. The Saint Louis University Androgen Deficiency in Aging Men (ADAM) Questionnaire. Dr. John Morley, a researcher with the Saint Louis University School of Medicine, developed the self-screening tool to help identify symptoms of low testosterone in men. Choose the responses below that best describe how you have been feeling.
1. Do you have a decrease in libido (sex drive)?
2. Do you have a lack of energy?
3. Do you have a decrease in strength and/or endurance?
4. Have you lost height?
5. Have you noticed a decreased “enjoyment of life”?
6. Are you sad and/or grumpy?
7. (MEN) No longer wake up with a morning erection?
8. (MEN) Are your erections less strong?
9. Have you noticed a deterioration in your ability to play sports?
10. Are you falling asleep after dinner?
11. Has there been a recent deterioration in your work performance?
12 Do you have a hard time sleeping through the night?
13. (WOMEN) Do you have a hard time getting aroused?
If you answer yes to question one or seven, or at least three of the other questions you may have low testosterone levels.
What is the side affects from low testosterone?
Increased body fat, Gyneomastia, Weak erections, Loss of muscle mass, Lack of libido, Lack of motivation, depression, memory loss, irritability, low self esteem, heart disease, diabetes, Hypertension, Osteoporosis, and even premature death. We need our hormones!!
We don’t have to be miserable as we age like many want us to believe. Contact us today to find out where your levels are and get them balanced.
Boston Testosterone/Core New England
Planning For A Baby? Obesity Linked To Changes In Sperm DNA Associated With Appetite
Listen up fellas: If you’re not going to get in shape for your own good, at least do it for the good of your future children. That’s because a new study has found obesity can change the genetic makeup of sperm cells in a way that may influence the appetite of future offspring. The same study found these changes may be reversed by losing weight, further highlighting how important good health is for not only moms-to-be, but also expectant fathers.
For the study, researchers from the University of Copenhagen in Denmark looked at the sperm of 13 lean men and 10 obese men in an effort to find biomarkers that would affect weight. Sperm samples from both groups turned up epigenetic markers in regions of the genome associated with the control of appetite, although they appeared differently between the two groups.
Epigenetic changes in the genome occur when lifestyle and the environment affect the way in which genes are expressed. Dr. Ida Donkin, co-author of the study, explained to Medical Daily in an email that our knowledge of epigenetic changes is still limited, but she believes these changes affect all of our genes differently. “Some features are more stable and others more susceptible to changes in the parent’s pre-conceptual lifestyle,” she wrote.
The epigenetic changes identified in the sperm suggests a parent’s lifestyle could affect their offspring’s appetite, and possibly even their body shape.
Change Is Possible
During the same study, researchers investigated whether significant weight change could also affect epigenetic markers. The team followed six men before and after they underwent gastric bypass surgery, and found an average of 4,000 structural changes to sperm cell DNA during the time period before surgery, directly after, and up to one year later.
Donkin explained that it’s difficult to say if the exact same effect would be seen in weight loss without surgery, she did note that her yet to be published research shows that just six weeks of exercise could bring about epigenetic changes in human sperm cells.
“Something tells us that weight-loss — no matter the tool you use to obtain it — will change the information of the sperm cells, and most likely influence the development, and risk of disease, of your children,” Donkin wrote.
Co-author Romain Barres, meanwhile, said such changes make sense from an evolutionary perspective. Extra weight has historically been advantageous and protected our ancestors from infections and famines. In the past, it would have been highly valuable for males to pass on their weight information to their offspring. “It’s only recently that obesity is not an advantage,” Barre said in a statement .
Father’s Health Is Important,Too
Although we know that a mother’s lifestyle, both before and during pregnancy, has an effect on the health of her unborn baby, this new study as well as others, have suggested the same may be true for fathers. A 2013 study from Duke University, for example, found fathers’ obesity could also contribute to epigenetic changes that increased their child’s risk of cancer. Another 2013 study on male mice, meanwhile, found that litters of male mice who were purposely denied folate experienced a 30 percent increase in birth defects .
“We have been telling mothers-to-be for years that they have to take care of their diet, to exercise and stay away from cigarettes and alcohol when pregnant or wanting to become so,” wrote Donkin. “This study tells us that the dads should also improve their lifestyle before conception, as their bad behavior might as well affect their children.”
It’s important to note that the study is small. In addition, although the researchers identified epigenetic changes in obese sperm associated with appetite, they did not actually prove that these changes were the reason children of obese men sometimes became obese. Still, the findings are significant in that they show not only does a man’s lifestyle affect the health of his future children, but also that weight loss can affect the way these genes are expressed.
Further research is needed to better understand the role that a father’s pre-conceptual health plays in that of their future offspring, but the team hopes their findings will help raise awareness of how important lifestyle factors are for both men and women prior to conception.
Source: Donkin I, Versteyhe S, Ingerslev LR, et al. Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans. Cell Metabolism . 2015
For for more information on our therapies please contact Clinic Director Charlie Blaisdell at CBlaisdell@CoreNewEngland.com
BTP/CORE New England / Core Medical Group
920 Washington Street
Norwood, MA 02062
There’s No Need To Wait For The New Year To Make A Resolution
Almost half of all Americans make New Year’s resolutions, and exercise and weight loss is always at the top of the list. That’s no surprise, considering that two-thirds of Americans are overweight or obese, and less than half get the recommend amount of exercise needed to stay healthy.
But a future plan to exercise can be used as an excuse to curl up in a ball of blankets and hibernate through the holidays, which could explain why some folks go into the new year with a little added heft. A 2000 study of 195 Americans found that people who were already overweight or obese gained an average of five pounds in the six weeks between Thanksgiving and Christmas, and that for all who gained holiday weight, these extra pounds made up more than half of the total weight they gained that year.
That’s why if you already know you need to exercise more — the government recommends 150 minutes of moderate activity per week with at least two strength training sessions — there’s no better time than the present to make a resolution about it, experts say.
Dr. Christine Whelan, a thought leader for AARP’s Life Reimagined program and a professor at the University of Wisconsin-Madison, says it’s a “good psychological trick” to mark a new beginning on a special date — say, your birthday, the new year or even just Monday morning. However, we’ve got to be careful that we’re not using this future date to justify delaying a life change.
“If you’re saying, ‘I will lose weight in the New Year’ as a way to allow yourself to binge during the holidays, think of what small step you can take right now — Dec. 1, perhaps — to get you on the right path for an even more successful new year,” Whelan told HuffPost.
In the spirit of resolution, we spoke to Whelan and two other experts about why you shouldn’t wait until the new year to start working on your goals now, and how to approach fitness so that you’ll greet 2016 with a strong exercise game already in place.
Be mindful about why you want to exercise more
Whelan says it’s easy to identify problems in our lives, but strategizing about ways to solve them is a lot harder. One way to know you’re making the right resolution for yourself is to first figure out why you’re doing it in the first place.
“Thinking about what you want to feel — and the why behind the change — makes you more likely to commit to the right resolution to achieve the desired outcome,” Whelan said.
Figuring out why you want to get in shape will also give you direction in how to go about it. Butch Nieves is a former winner of the Mr. America and Mr. USA bodybuilding contests and a personal trainer and leader at the New York Fit Body Boot Camp. He agreed that the first thing people should do when they decide they want to start exercising again is to really contemplate why they want to do it in the first place.
“First, know your ‘why’: Why did you decide to train?” Nieves said. “Your ‘why’ will dictate what your program should be, and what your sense of urgency should be.”
Set some realistic goals and timelines
Research shows that writing down your goals makes you more likely to achieve them. But if those goals are too broad, big or unrealistic, you may find yourself discouraged after failure or burnout, warns Joe Ardito of Fit Crush NYC.
It may seem counterintuitive to start small, but remember that you want to set yourself up for success, not injury or burnout.Joe Ardito of Fit Crush NYC
“Being realistic about your fitness goals can help you both mentally and physically,” Ardito said. “It may seem counterintuitive to start small, but remember that you want to set yourself up for success, not injury or burnout.”
To maximize success, Whelan suggested picking just one goal to fulfill from now until the end of the year — not a whole list of big changes.
“Maybe you want to exercise several times a week, despite the holiday parties,” she said. “Maybe you want to focus on your relationships by putting devices away each evening.”
Make a workout plan
Ardito says there are four building blocks of fitness: flexibility, strength training, cardiovascular training and nutrition. The more you plan to tackle each of these pillars before you hit the gym, the less likely you are to waste time and get distracted, he says.
If you want to get in the gym and get out fast, a combo of circuit training and high-intensity interval training will accomplish the most in the shortest amount of time, Nieves says. Alternating periods of vigorous exertion and active recovery have been shown to increase the number of calories burned, both during the workout and afterward.
But, if going to the gym isn’t an option right now, brainstorm other physical activity goals you can set, Ardito suggests.
“Bike to work, take the stairs rather than the elevator and walk a few times around the block on your lunch break,” he suggests.
Get some friends involved
Whelan adds that it isn’t enough to write down your goals; telling others about them and bringing them alongside you can increase your chances of actually staying on track.
“Research shows that couples who go on a diet together are more likely to lose weight and keep it off,” she writes. “Find an exercise partner or an accountability partner for any goal.”
“Surround yourself with an uncompromising group that only give and demand the best,” Nieves adds. “A 2011 study published in Psychology of Sport and Exercise found that the exercise habits of people you know have a positive influence on your own exercise habits.”
Be kind to yourself and others
Finally, it’s important to keep in mind that exercise resolutions aren’t just relentless, never-ending self-improvement projects to work on the way you look. Sure, you may want to feel sexier, or you may want to fit into the clothes you like. But maybe you just want to be able to ride a bike with your grandkids, Nieves says, or be able to use a flight of stairs without having a heart attack.
Your heart will get you through the tough times and through the negativity and disappointments that you may encounter from time to time.Butch Nieves of New York Fit Body Boot Camp
The point is that resolutions to exercise are ultimately resolutions to be there — for yourself and your loved ones — for as long as possible, in a meaningful and joy-filled way. Nieves frequently tells his clients that the best thing about their bodies isn’t their butt, or their toned arms. Instead, it’s their heart.
“My job, as a coach, is to get through your mind and into your heart,” he said. “Your heart will get you through the tough times and through the negativity and disappointments that you may encounter from time to time.”
“When you have heart, you will be strong and happy and there is nothing that will stop you!” he concluded.
And why not use that big heart of yours to help others? Whelan advises us to think bigger about our exercise goals to consider the lasting impact we want to have on other people.
“Most of us focus our New Year’s resolutions on all the little things about ourselves that we want to change: Go to the gym every day, lose weight, eat better,” Whelan said. “This year, consider adding an item to that resolutions list that’s bigger than you: volunteering for a specific charity, serving your community, anything that will take you out of yourself for a little while.”
Don’t wait for New Year’s, start today!
For for more information on our therapies please contact Clinic Director Charlie Blaisdell at CBlaisdell@CoreNewEngland.com
BTP/CORE New England / Core Medical Group
920 Washington Street
Norwood, MA 02062